nph insulin การใช้

• This was followed by the development of the long acting NPH insulin in the 1940s.
• NPH insulin may be combined with faster acting insulin to allow more accurate dosing and better blood sugar level control.
• In 1946, Nordisk was able to form crystals of protamine and insulin and marketed it in 1950 as NPH insulin.
• Compared with NPH insulin, the risk for all hypoglycemia with insulin detemir was reduced by 47 % ( P < 0.001 ) and nocturnal hypoglycemia by 55 % ( P < 0.001 ).
• The proper order for withdrawing NPH insulin and fast-acting insulin into the same syringe can be remembered by the mnemonic " clear before cloudy ", or fast acting clear insulin first, followed by NPH ( cloudy ).
• According to the manufacturer's website, the insulin's action profile was long and flat in dogs, but in cats was similar to that of NPH insulin, and lowered blood sugar quickly, but for only about 6 8 hours.
• NPH insulin has the advantage that it can be mixed with an insulin that has a faster onset to complement its longer lasting action, which is the primary reason NPH remains on the market today, because manufacturers sell a variety of premixed insulin formulations.
• In both groups, 70 % of participants achieved an HbA 1c of 7.0 %, but the proportion achieving this without hypoglycemia was higher with insulin detemir than with NPH insulin ( 26 vs . 16 %, P = 0.008 ).
• Mean weight gain was 1.2 kg with insulin detemir and 2.8 kg with NPH insulin ( P < 0.001 ), and the difference in baseline-adjusted final weight was  1.58 ( P < 0.001 ) ."
• Whether these observed differences represent true differences in the effects of LEVEMIR and NPH insulin is not known, since these trials were not blinded and the protocols ( e . g ., diet and exercise instructions and monitoring ) were not specifically directed at exploring hypotheses related to weight effects of the treatments compared.
• 2 . http : / / www . springerlink . com / content / 6lktug1r2exurq0j / ? p = af5e2f613a0f4c6690f8fdc920f48bd6 & pi = 5, ( 2007 ) Insulin analogues ( insulin detemir and insulin aspart ) versus traditional human insulins ( NPH insulin and regular human insulin ) in basal-bolus therapy for patients with Type 1 diabetes, " Journal Diabetologia ", volume 47, number 4 / April, 2004.